Immunohistochemistry Kits and Reagents
Abcam TripleStain IHC Kit: M&M&R on Human tissue (DAB, AP/Red & HRP/Green), 60ML
Abcam's TripleStain IHC kit (ab183286) is designed to use with user supplied two mouse primary antibodies and one rabbit primary antibody to detect three distinct antigens on a single human tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
Biocare Medical, LLC Betazoid DAB Buffer - 25 ml
3, 3’ Diaminobenzidine (DAB) is a widely used chromogen for immunohistochemical staining. Betazoid DAB Buffer is one of two components used for DAB staining. This product is intended to be used in combination with Betazoid DAB Chromogen (BDB900C) available in the Betazoid DAB Chromogen Kit (BDB2004). The color of the chromogen buffer mixture may vary from colorless to pale brown. Staining properties are not affected by the color of the chromogen buffer mixture. In some cases, antibody titers may increase as much as 2-fold using this DAB system. Betazoid DAB can be used both manually and on automated stainers.
Biotium Tenascin(T2H5), CF594 conjugate, 0.1mg/mL
In Western blotting, this antibody reacts with two bands of ~MW of 210 kDa and 300 kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linkedhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue
ABclonal Technology Phospho-p38 MAPK-T180 Rabbit pAb
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Medchemexpress LLC P38-α MAPK-IN-1 | 443913-15-3 | 99.7% | 477.60 | 5 MG
p38-α MAPK-IN-1 is an inhibitor of MAPK14 (p38-α) that demonstrates inhibitory activity in both EFC displacement and HTRF assays. It also effectively inhibits LPS-induced tumor necrosis factor-alpha (TNF-alpha) production in THP-1 cells. This product is intended for research use only.
- Inhibits MAPK14 (p38-α)
- Effective in EFC displacement and HTRF assays
- Inhibits LPS-induced tumor necrosis factor-alpha (TNF-alpha) production
ABclonal Technology Phospho-p38 MAPK-T180/Y182
This gene encodes a member of a family of protein kinases that are involved in the integration of biochemical signals for a wide variety of cellular processes including cell proliferation differentiation transcriptional regulation and development The encoded protein can be activated by proinflammatory cytokines and environmental stresses through phosphorylation by mitogen activated protein kinase kinases (MKKs) Alternative splicing results in multiple transcript variants [provided by RefSeq Mar 2014]
ABclonal Technology Phospho-TDP-43/TARDBP-S409/S410 Rabbit pAb
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Cayman Chemical S-p38 MAPK InhIbItr III 5mg
A methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 µM in vitro); potently blocks the release of TNF-α and IL-1β from human peripheral blood mononuclear cells (IC50s = 0.37 and 0.044 µM, respectively)
Seracare Life Sciences Inc HISTOMARKORANGE HRP SUBS KIT
Metal enhanced DAB technology permits detection of extremely low concetrations of tissue antigens. This kit provides a sensitive means for detecting peroxidase labeled antibodies and conjugates. HistoMark Orange contains nickel enhanced DAB that produces an orange-red DAB polymer and also exceeds the sensitivity of DAB alone. The kit contains the nuclear counterstain, Contrast GREEN, a solution of methyl green that contrasts sharply with orange. Blocking solution is provided to prevent endogenous peroxidase activity. The precipitates from HistoMark Orange are alcohol and xylene insoluble, allowing section to be mounted in aqueous or xylene-based mounting media.
OriGene Desmin (DES) CytoSection, Positive Control For IHC, ICC, & ISH, 25 Slides
The Origene Technologies Desmin (DES) CytoSection is a crucial tool for researchers, providing validated positive controls for detecting Desmin expression in immunohistochemical, immunocytochemical, and *in situ* hybridization applications. This product includes 25 FFPE slides containing HEK293T cells with transient overexpression of human Desmin, ensuring reliable and accurate experimental results, distinguishing it from other controls with its specific targeted application.
Biocare Medical, LLC intelliPATH FLX DAB Chromogen Kit - 80 ml
3, 3’ Diaminobenzidine (DAB) is a widely used chromogen for immunohistochemical staining and immunoblotting. When in the presence of peroxidase enzyme, DAB produces a brown precipitate that is insoluble in alcohol and xylene. This product comes in a two-component system consisting of a liquid stable DAB chromogen and DAB substrate buffer. The color of the chromogen may vary from pale brown to orange. However, this does not interfere with staining properties. intelliPATH FLX DAB is a very stable and superior formulation. In some cases, antibody titers may increase by two-fold. intelliPATH FLX DAB can be used both manually and on automated stainers.
Abcam TripleStain IHC Kit: R&R&M on human tissue (DAB, AP/Red & Green/HRP), 60ML
Abcam's TripleStain IHC Kit (ab183288) is designed to be used with one mouse and two rabbit primary antibodies, supplied by the user, to detect three distinct antigens on human tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
Abcam DoubleStain IHC Kit: G&M on human tissue (Green/HRP & AP/Red), 60ML
Abcam's DoubleStain IHC kit (ab183272) is designed to use with user supplied goat and mouse antibodies to detect two distinct antigens on human tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
Abcam TripleStain IHC Kit: M&R&G on human tissue (DAB, AP/Red & DAB/Ni), 18ML
Abcam's TripleStain IHC Kit (ab183291) is designed to be used with user-supplied goat, mouse and rabbit primary antibodies to detect three distinct antigens on a single human tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
Biocare Medical, LLC Hot Rinse, 25X - 500 ml
Hot Rinse, 25X is intended for laboratory use in immunohistochemistry procedures on formalin-fixed paraffin-embedded (FFPE) tissues to ensure complete deparaffinization. Hot Rinse is sodium azide and thimerosal free, non-toxic, non-flammable and odorless. After deparaffinizing tissues in Reveal, Universal or Borg Decloaker, a subsequent hot rinse ensures complete deparaffinization. It is specially designed for use with Biocare Decloaking Chamber and is also compatible with other commercial heat retrieval deparaffinization solutions.